Latest Research News

New Possibility of Molecularly Targeted Therapy for Lung Cancer with KRAS Gene Mutation

[May 6, 2016] It is demonstrated that combination treatment with MEK inhibitor and either FGFR1 inhibitor or ERBB3 inhibitor is effective in screening tests using cultured cell lines and resulted in tumor regression in model mice.

Transcription Factor Sox11 is Identified to be a Suppresser of Cerebral Cortex Development

[May 25, 2016] The transcription factor Sox11 was identified as a suppresser of the dendritic morphogenesis and, therefore, the cerebral cortex development.

New Diamond Device Developed with the Use of Ferroelectrics

[June 13, 2016] A new diamond-based Field Effect Transistor, FET, with Ferroelectric gate insulator has been successfully fabricated by the use of organic ferroelectrics VDF-TrFE.

Cadaveric Dura Mater Grafting and Subpial Aβ Deposition and Meningeal Amyloid Angiopathy

[June 17, 2016] The team led by researchers of Kanazawa University reports pathological changes in the brain of patients with Creutzfeldt-Jakob disease developing after cadaveric dura mater grafting.

Unveiling Invasion History of the Signal Crayfish in Japan

[July 4, 2016] A combination of high genetic diversity in older populations of the invasive range and rapid adaptation has manifested as larger chela in newer invasions, likely contributing to invasion success in Japan.

Identification of a key gene to make the distribution base of senses in the brain

[July 6, 2016] The research team of Brain/Liver Interface Medicine Research Center, Kanazawa University, Japan has identified a gene that is essential to the formation of the thalamus.

Mechanism underlying formation of folds of the cerebral cortex – a clue to higher brain functions

[July 12, 2016] The mechanism of fold formation, which used to be difficult to investigate, was elucidated by the technique developed by the present researchers, and Tbr2 gene was identified to be essential for the fold formation.

Novel Method for “Power Generation by Utilizing Waste Heat”, a Theoretical Prediction

[July 16, 2016] Researchers of Kanazawa University discovered, through computer simulation, the possibility of generation of enormous thermoelectric effect by skyrmion, a whirl-like structure, produced by the spins of electrons.

Discovery of Actions, so far Unknown, of DPP-4 Inhibitors, a Drug for Diabetes

[July 21,2016] It is discovered that DPP-4 (dipeptidyl peptidase-4) inhibitors, most frequently used for treatment of diabetes in Japan, exert the actions, so far unknown, to attenuate obesity-induced inflammation of adipose tissues and insulin resistance.

Emergency communication by mobile phone augments the survival of out-of-hospital cardiac arrest victims

[Aug22, 2016] Investigation on approximately 3000 out-of-hospital cardiac arrest (OHCA) cases in Ishikawa Prefecture from 2012 through 2014 indicated that the survival rate was better with emergency communication by mobile phone than by fixed telephone.

Identification of neurons that determine the length of a day, the period of circadian rhythm

[Aug 25, 2016] Vasopressin-producing neurons have been found to determine the period length of the biological clock that generates circadian rhythm (the length of a day for the individual organism).

Characteristics of Brain Activities in Visual Reasonings in Autistic Children: a MEG Study

[Sep 16, 2016] The study has revealed for the first time that with AS children, the higher the functional connectivity of the visual occipital area with other areas of the brain through the gamma band, the higher the ability to perform visual reasoning tasks.

Development of Specific Antibodies to HGF – for Elucidation of Structure and Signaling

[Sep 9, 2016] Hepatocyte Growth Factor (HGF) regulates tissue regeneration and cancer progression, and is a drug candidate for treatment of ALS (amyotrophic lateral sclerosis). A panel of functionally different monoclonal antibodies to HGF has successfully been generated.

Special brain activities while mother and autism spectrum disorder child gaze each other

[Oct 10, 2016] Special activities in the brains have been discovered while a child with autism spectrum disorder and the mother are gazing each other by the utilization of special equipment based on magnetoencephalography applicable to both child and mother simultaneously.

Sulforaphane, a phytochemical in broccoli sprouts, ameliorates obesity

[Feb 17, 2017] In the present study, experiments with mice demonstrate that sulforaphane ameliorates obesity, the conclusion based on the two functions of sulforaphane newly uncovered.